Study: Relationship Between Heavy Metals and Autism

What do autism and spectrum disorders in tiny children have in common with older people suffering with dementia? Their brains are chockful of heavy metals. These heavy metals be may exist in our environment naturally, or as impurities introduced through raw materials that are used in the production process -- of anything from cosmetics, household materials like paint, to the water you consume.

What Are Heavy Metals?

By definition, heavy metals are elements that can elicit adverse effects on the central nervous system and cognitive function. It is a huge and growing concern with far-reaching implications for human health, especially for the development of young children.

The most common heavy metals are elements, such as lead (Pb), mercury (Hg), cadmium (Cd), arsenic (As), and chromium (Cr), which can exert toxic effects on living organisms at even very low exposure levels.

When you are poisoned by heavy metals, you suffer severe and long-term consequences on the brain, resulting in cognitive impairment. Chronic exposure to heavy metals may interrupt the development of physical, muscular, and neurological conditions, that look a lot like diseases such as Parkinson’s and Alzheimer’s disorders.

The Study: The Relationship between the Level of Copper, Lead, Mercury and Autism Disorders: A Meta-Analysis

We know about the likelihood of a possible relationship between the concentrations of copper, lead, and mercury and autism. Researchers in this study wanted to review various studies to determine the relationship between the concentrations of these elements and autism by meta-analysis.

They eventually chose 18 out of 95 selected studies, involving 2–16-year-old children from different countries from 1982 to 2019.

The Results

The results were significant.

In these 18 studies, 1797 patients (981 cases and 816 controls) aged 2 to 16 years were examined. Concentration of the samples (blood, hair, and nails) for both case and control groups was evaluated. There was no significant relationship between copper concentration and autism (SMD (95% CI): 0.02 (− 1.16,1.20); I2=97.7%; P=0.972); there was a significant relationship between mercury concentration and autism (SMD (95% CI): 1.96 (0.56,3.35); I2=98.6%; P=0.006); there was also a significant relationship between lead concentration and autism (SMD (95% CI): 2.81 (1.64,3.98); I2=97.8%; P=0.000).

These heavy metals were found in various parts of the children through tests, especially in their blood plasma and nails. You can check out the concentrations of copper, mercury and lead in samples of hair, nails, and plasma of the children with autism and a control group in studies— the results of the meta-analysis are presented in Table 1 of the study.

Due to the chemical properties of certain metals, excessive metal exposure can cause brain abnormalities.

The study was published in Pediatric Health Medicine.

Why is this study important?

The review examined multiple studies and found a very strong link between lead and mercury concentration and autism.

Yet, are you aware of just how pervasive these toxic heavy metals are in our environment? It's found in things from cosmetics, interior decor and materials like paint, down to our water supply and quality of air.


Compared with adults, children are more exposed to environmental toxic elements and also absorb them at a higher rate.


On the other hand, the chance of warding off elements’ toxicity in children is less than adults.

Evidence of mercury’s toxicity has been growing for decades, and in recent years is focused on the metal’s association with neurodevelopmental disorders, including autism spectrum disorder (ASD).

Brain health is what makes us happy, creative, vital individuals. We can build all the muscle we want and look good on the outside, but it is our super powerful computing system that powers how we live every day. If you are serious about averting neurological crises and general degeneration, prioritise eliminating every source of heavy metals in your own home.

References & Notes:

  • Jafari Mohammadabadi H, Rahmatian A, Sayehmiri F, Rafiei M. The Relationship Between the Level of Copper, Lead, Mercury and Autism Disorders: A Meta-Analysis. Pediatric Health Med Ther. 2020;11:369-378
    https://doi.org/10.2147/PHMT.S210042 Link: https://www.dovepress.com/the-relationship-between-the-level-of-copper-lead-mercury-and-autism-d-peer-reviewed-fulltext-article-PHMT

  • Mercury is a risk factor for autism. Mercury is considered as a risk factor for autism since, according to previous studies, it has been recognized as a neurotrophic toxin. Check out the study here.